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Introduction
Cell phones and cell phone towers have been the subject of much concern in the media about potential health issues. There have been a number of highly sensational statements from certain individual scientists and doctors about the risk of cancer from cell phone use. Some have gone so far as to claim the cell phone use is as harmful to health as smoking. These wild claims are not supported by the scientific evidence.
In fact studies to date have found no solid evidence for any link between cell phone use and cancer. Two basic types of epidemiological studies are have been used for assessing the risk of cell phones causing brain cancer. These are case-control and the cohort studies. For cell phones case control studies, patients with brain cancer are identified. These patients are then either given a questionnaire, or are interviewed, and are asked to recall from memory how much they used their cell phones over their lifetimes. Their answers are compared with a control group that does not have brain cancer. This type of study is subject to a number of potential sources of error. The most serious is "recall bias". Patients with brain cancer who have heard that cell phones might cause brain cancer may unconsciously overstate their past use. The cancer may also have affected their memory. In fact a case control study is only as good as people's memory.

The cohort type of study is much more robust. In this type of study a large number of subjects are identified before they have any illness. Their cell phone use is monitored for a number of years. At the end of the study, the cell phone usage of subjects who develop brain cancer is compared with those who are healthy.  One of the best studies to date was a "retrospective" cohort study of 420,000 cell phone users in Denmark. Some had been using their cell phones for over 15 years. Researchers had access to both their cell phone and their medical records. There was no possibilikty of recall bias. No evidence of increased risk for brain cancer was found (see study #2 below).

Figure 2
Another strong piece of evidence is the fact that there has been no increase in the rates of brain cancer in the population. The European SCENIHR and the US National Cancer Institute (NCI) have issued statements to this effect. The following quote was taken from the latest Jan. 2009 report "Health Effects of Exposure to EMF" by the SCENIHR advisory committee of the European Commission (P. 24, also see Fig. 1 above): "Altogether, the data collected until now provide no evidence of an increased brain tumor risk. This is consistent with the observation that no visible increases are seen in the age specific incidence rates of tumors of the central nervous system in the Nordic countries over the last decade"  In a recent Bulletin (Sept 23, 2008) the NCI stated: "There was no upturn in the incidence of brain or other nervous system cancers between 1987 and 2005, according to data from NCI's Surveillance, Epidemiology and End Results program". Fig. 1 above taken from P. 24 of the SCENIHR report shows that the incidence of brain cancer has remained constant from 1985 to 2004 - which covers the entire period since cell phones were introduced. Fig 2 was generated from the latest data on brain cancer and other nervous system cancer from the NCI's SEER database and covers the years 1975 - 2007. The vertical axis is annual cases per 100,000 all races & sexes.

Important studies
Included below are links to a number of studies and documents related to cell phones.
1. New Danish Cell Phone study:
There was no substantial change in brain tumor incidence among adults 5 to 10 years after cell phone usage sharply increased, according to a new brief communication published online December 3 in the Journal of the National Cancer Institute. These findings are essentially the same as those from the NCI and SCENIHR cited above. Study summary.
2. Danish Cell Phone Study: This "retrospective" cohort study was published in the Dec. 6, 2006 issue of the Journal of the National Cancer Institute. This is probably the most reliable epidemiological study on cell phones and cancer to date. From the abstract: The widespread use of cellular telephones has heightened concerns about possible adverse health effects. The objective of this study was to investigate cancer risk among Danish cellular telephone users who were followed for up to 21 years. Methods: This study is an extended follow-up of a large nationwide cohort of 420 095 persons whose first cellular telephone subscription was between 1982 and 1995 and who were followed through 2002 for cancer incidence. Conclusions: We found no evidence for an association between tumor risk and cellular telephone use among either short-term or long-term users. Moreover, the narrow confidence intervals provide evidence that any large association of risk of cancer and cellular telephone use can be excluded.
3. The Interphone series of case control studies are an international collaborative effort coordinated by the IARC to assess the health risks of cell phones. Groups from 13 countries including Australia, Canada, Denmark, Finland, France, Germany, Israel, Italy, Japan, New Zealand, Norway, Sweden and the UK are conducting a series case-control studies for a variety of cancers. The results to date for the Interphone series of studies do not show any clear increased health risk. However research is ongoing for long term use greater than 10 years. The final report has been delayed. There has been much speculation in the media fueled by alarmists about this study. One of the researchers participating in the Interphone study stated recently that: "
the study has not yet confirmed whether or not there is an increased risk of cancer from mobile phone use." "There is ... absolutely no information circulating at the moment that is accurate and correct with respects to the results of that study." It is important to understand that a difficulty with this type of study is that it relies on brain cancer patients to recall how much they used their cell phones over their lifetimes. Patients who have brain cancer, and have heard media reports of a possible association between cell phones and brain cancer, may unconsciously overstate their cell phone use and skew the results. This is what is termed recall bias. The Danish cell phone study is much more robust because it used actual cell phone records.
News:
The final Interphone Study has just been released See our special web page..

Statements about cell phones & health from public health authorities
The following is a list of links to statements issued by the public health authorities of various countries about cell phones and health. The message from each of them is essentially the same. There is no significant evidence to date of harmful health effects due to cell phones. However research is on going for longer term use. It should be noted that available statistics for the US and Canada (up to 2007) show a slight decrease in the annual number of newly diagnosed malignant brain tumors.
1. The American Cancer Society statement on cell phones & health.
2. US FDA statement on cell phones & health.
3. US National Cancer Institute NCI statement on cell phones & health and a recent update: Cell Phones and Brian Cancer: What do we know?
4. US Centers for Disease Control CDC statement on cell phones and health.
5. Health Canada information document on Safety and Safe Use of Cellular Phones.
6. The SCENIHR advisory committee of the European Commission has published an updated 83 page report dated Jan. 2009 entitled Health Effects of Exposure to EMF. The following is a quote from the Abstract P. 4. "
It is concluded from three independent lines of evidence (epidemiological, animal and in vitro studies) that exposure to RF fields is unlikely to lead to an increase in cancer in humans. However, as the widespread duration of exposure of humans to RF fields from mobile phones is shorter than the induction time of some cancers, further studies are required to identify whether considerably longer-term (well beyond ten years) human exposure to such phones might pose some cancer risk."
7. The SCENIHR
advisory committee of the European Commission has published summary for the public on the issue of EMF & health dated March 2007. The following is a quote concerning cell phones and cancer risk: "Research indicates that a person who has used a mobile phone for up to 10 years does not have a higher risk of brain tumors or other cancers in the skull. This also appears to be the case for someone who has used a mobile phone for more than 10 years but more research is needed to confirm this."
8. The Health Council of the Netherlands published a 96 page report on Mobile Phones, an evaluation of health effects. The following statement is taken from the Executive Summary: "
Mobile telecommunication has developed considerably in recent years: to date over half the population of the Netherlands posses a mobile telephone. Nevertheless, concerns also grow, particularly as to whether exposure to electromagnetic fields from antennas and mobile telephones can adversely affect health. In this advisory report, the Electromagnetic Fields Committee of the Health Council of the Netherlands provides, on the basis of the scientific literature, an overview of various aspects that may play a role. The Committee comes to the conclusion that there is at present no reason for concern. However, since mobile telephony leads to widespread electromagnetic field exposure and relatively little knowledge exists on, especially, long term effects; it indicates areas for further research."
Papers by Hardell et al.
Hardell et al. have been the authors of a number of studies that claim to have found an increased risk of certain brain cancers associated with long term use of cell phones. Hardell himself is one of the lead authors of the Bio-Initiative Report. Some of the Hardell et al. studies have been criticized in the scientific community because of "recall bias". All of Hardell's studies are of the case control type. Patients who have been diagnosed with brain cancer fill in a questionnaire in which they are asked to remember how much they used their cell phones. The US FDA had this to say about Hardell et al.'s methodology: "The results reported by Hardell et al. are not in agreement with results obtained in other long term studies. Also, the use of mailed questionnaire for exposure assessment and lack of adjustments for possible confounding factors makes the Hardell et al. study design significantly different from other studies." The SCENIHR scientific advisory group to the European Commission stated that this study was: "non-informative because of inappropriate exclusion criteria and combination of studies". Another scientific consortium advising the European Commission, the EMF-NET issued a formal statement criticizing the same recent Hardell et al. paper in which they questioned its statistical methods.

Hardell et al.'s latest study, just published in the journal Pathophysiology, appears to use a methodology that is similar to their previous studies. The new Hardell et al. paper actually criticizes the Interphone series of studies, which is an international collaborative effort coordinated by the IARC to assess the health risks of cell phones. It even suggests that cancer patients in the Interphone studies underestimated their use of cell phones, whereas in Hardell et al.'s studies they did not. This clearly indicates the main problem with this type of study, namely recall bias. The results to date for the Interphone studies do not show any increased health risk. The latest Hardell et al. paper also excluded two very important studies from their meta analysis. These studies did an objective analysis of the medical records of 420,000 cell phone users in Denmark and found no evidence for any increased cancer risk. These Danish studies did not use subjective questionnaires. Hardell himself has earned fees as an "expert" witness in litigation against cell phone companies. In 2002 his testimony in a lawsuit which sought $800M in damages for a single brain cancer patient was resoundingly rejected by the judge for lacking in scientific credibility.

It should be noted that Hardell et al. have promoted their studies in the mass media with the claim that they have been published in scientific peer reviewed journals. The implication is that their studies have a high degree of scientific credibility. It should be noted that there are literally thousands of scientific journals. There are wide differences in editorial standards and credibility among the various journals. Just because a study is published in a "peer reviewed" journal, does not necessarily mean that its findings are valid. Hardell et al.'s papers have been strongly criticized by a number of public health bodies. They are not generally accepted by the scientific community.


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